{"id":39976,"date":"2021-06-07T08:11:33","date_gmt":"2021-06-07T14:11:33","guid":{"rendered":"https:\/\/www.uchealth.org\/today\/?p=39976"},"modified":"2023-07-03T09:56:39","modified_gmt":"2023-07-03T15:56:39","slug":"covid-19-vaccine-trial-for-children-under-age-12-launching-at-childrens-hospital-colorado","status":"publish","type":"post","link":"https:\/\/www.uchealth.org\/today\/covid-19-vaccine-trial-for-children-under-age-12-launching-at-childrens-hospital-colorado\/","title":{"rendered":"COVID-19 vaccine trial for children under age 12 launching at Children\u2019s Hospital Colorado"},"content":{"rendered":"
<\/div>
\"Children
Hope is surging that children under age 12 soon could get vaccines to prevent COVID-19. A new clinical trial at Children’s Hospital Colorado will provide key information. Photo: Getty Images.<\/figcaption><\/figure>\n

Hopes are soaring that children under age 12 soon will be able to get vaccines to prevent COVID-19.<\/p>\n

And, research taking place at Children\u2019s Hospital Colorado<\/a> on the Anschutz Medical Campus<\/a> will help provide key answers. Doctors at Children\u2019s Colorado plan to test the Pfizer BioNTech COVID-19 vaccine this summer on children ages 5 to 11. Later, the team is expected to test the vaccine on babies and children, ages 6 months to 4 years old.<\/p>\n

The results will be closely watched since anyone age 12 and older easily can get vaccines now at walk-in clinics<\/a> and parents of younger children are eager to protect their families too.<\/p>\n

\"Dr.
Dr. Eric Sim\u00f5es, a pediatric infectious disease expert who is leading the Pfizer COVID-19 vaccine clinical trial at Children\u2019s Colorado.<\/figcaption><\/figure>\n

\u201cThere\u2019s overwhelming interest in COVID-19 vaccines for children,\u201d said Dr. Eric Sim\u00f5es<\/a>, a pediatric infectious disease expert who is leading the Pfizer clinical trial at Children\u2019s Colorado.<\/p>\n

Getting younger children vaccinated as soon as possible<\/a> will allow kids to return to full-time, in-person school as soon as possible and help end the pandemic.<\/p>\n

\u201cIt\u2019s crucial that children get vaccinated,\u201d said Dr. Lalit Bajaj<\/a>, a pediatric emergency medicine specialist, who is helping oversee the Pfizer study and other vaccine trials at Children\u2019s Colorado.<\/p>\n

As the pandemic is easing in the U.S., the majority of COVID-19 cases in Colorado and the U.S. now are afflicting younger people.<\/p>\n

\u201cWe still see kids sick with COVID-19,\u201d Bajaj, who is also a professor of Pediatrics and Emergency Medicine<\/a> at the University of Colorado School of Medicine<\/a>. \u201cSome of these children are very, very sick. There\u2019s an impact on the patients themselves and on the community as a whole.\u201d<\/p>\n

Sim\u00f5es and Bajaj said the newest COVID-19 variants are highly transmissible, meaning they spread very easily, especially in children<\/p>\n

\u201cWe really need to get a significant number of children vaccinated in order to get ahold of this pandemic,\u201d Bajaj said. \u201cThen we can get back to some normalcy.\u201d<\/p>\n

\u201cThese vaccines are crucial for society as well as for the kids themselves,\u201d said Sim\u00f5es, who is also a professor of\u00a0Pediatrics at the University of Colorado School of Medicine<\/a> and a professor of Epidemiology Colorado School of Public Health<\/a>.<\/p>\n

Vaccines so popular that volunteers enter a lottery<\/strong><\/h2>\n

The Children\u2019s Colorado Pfizer clinical trial site is one of about 80 across the country. For the study on children ages 5 to 11, doctors at Children\u2019s Colorado plan to give vaccines or placebo to about 250 children. Across the country, about 4,600 children will be involved in the study.<\/p>\n

Parents have been so excited to have their children participate in clinical trials for COVID-19 vaccines that Pfizer created a website where parents could sign their children up as potential volunteers. Study managers in Colorado then conducted a lottery to select participants.<\/p>\n

\"Dr.
Dr. Lalit Bajaj, a professor of Pediatrics and Emergency Medicine at the University of Colorado School of Medicine.<\/figcaption><\/figure>\n

Sim\u00f5es said the roster of volunteers for the clinical trial is already full.<\/p>\n

As with the adult clinical trials, researchers around the world and in Colorado have worked hard to include a diverse pool of study participants in clinical trials.<\/p>\n

\u201cThe groups that have been particularly affected throughout the pandemic have been minority populations,\u201d Sim\u00f5es said. \u201cWe\u2019ve done a lot of outreach to different minority populations: Black Americans, Latin Americans and Asians.\u201d<\/p>\n

When the research begins in Colorado, study participants will receive their first and second doses of the vaccine or a placebo three weeks apart, just like adults. Participants will be enrolled in this trial for approximately two years to determine how the vaccines work in protecting children from COVID-19 over the long term.<\/p>\n

The researchers expect the vaccines to work as well with young children as they have in adults and teens.<\/p>\n

\u201cIt\u2019s really well tolerated,\u201d Bajaj said.<\/p>\n

How the COVID-19 vaccine clinical trial at Children’s Hospital Colorado will work<\/strong><\/h2>\n

Children who volunteer for the study will receive either the real Pfizer vaccine or a placebo. In adults, half of the study volunteers received the vaccine while half received a placebo. In the clinical trials for children, more volunteers get the real vaccine. Two children will get the real vaccine for every one child who receives the placebo.<\/p>\n

The children who participate will return to Children\u2019s Colorado for follow-up visits so researchers can test the level of antibodies in their blood. The young volunteers need to be comfortable receiving vaccines and giving blood.<\/p>\n

After six months of follow-up, families will learn if their children received the real vaccine or a placebo. This is known as \u201cunblinding.\u201d At that time, any child who received a placebo will be able to get the study vaccine. Unblinding will occur earlier if federal health officials grant an Emergency Use Authorization to allow the Pfizer vaccines for children ages 5 to 11.<\/p>\n

The research at Children\u2019s Colorado is known as a combined Phase 2-3 study. Researchers are trying to learn if a larger group of young children have similar antibody responses to older kids, teens and adults. Among adults and teens, the COVID-19 vaccines have been excellent, preventing serious illness and hospitalizations as much as 95% of the time, while producing excellent immune responses.<\/p>\n

Sim\u00f5es is confident that the clinical trials will prove that the vaccines are as safe for young children as they are for teens and adults.<\/p>\n

\u201cThere is no reason to think that something unsafe is going to happen when children receive vaccines,\u201d Sim\u00f5es said. \u201cThese vaccines appear to be very safe.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

Hopes are soaring that children under age 12 soon will be able to get vaccines to prevent COVID-19. And, research taking place at Children\u2019s Hospital Colorado on the Anschutz Medical Campus will help provide key answers. Doctors at Children\u2019s Colorado plan to test the Pfizer BioNTech COVID-19 vaccine this summer on children ages 5 to […]<\/p>\n","protected":false},"author":2123,"featured_media":39984,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[8],"tags":[4859,4860,9069,278,2600,351,4781],"class_list":["post-39976","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-coronavirus","tag-covid-19","tag-covid-19-vaccine","tag-family-medicine","tag-pediatic-care","tag-primary-care","tag-research-in-health-care"],"acf":[],"yoast_head":"\nCOVID-19 vaccine trial launches at Children's Hospital - 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