{"id":4934,"date":"2016-01-20T00:00:00","date_gmt":"2016-01-20T07:00:00","guid":{"rendered":"https:\/\/www.uchealth.org\/today\/2016\/01\/20\/daughter-of-uchealth-charge-rn-honored-for-groundbreaking-cancer-research\/"},"modified":"2023-10-11T12:03:30","modified_gmt":"2023-10-11T18:03:30","slug":"daughter-of-uchealth-charge-rn-honored-for-groundbreaking-cancer-research","status":"publish","type":"post","link":"https:\/\/www.uchealth.org\/today\/daughter-of-uchealth-charge-rn-honored-for-groundbreaking-cancer-research\/","title":{"rendered":"Daughter of UCHealth charge RN honored for groundbreaking cancer research"},"content":{"rendered":"
<\/div>

Do you remember what you wanted to be when you grew up? Chances are your adult self wound up\u00a0with different ideas than your five-year-old self. Not so for Allison Cleary, the daughter of Lone Tree Health Center charge nurse Kathleen Cleary, RN. Allison, now 30, knew she wanted to be a doctor from the time she was a little girl, and has never wavered with her choice.<\/p>\n

\u201cI remember when Allison was in second or third grade and she got an assignment to do a self-portrait,\u201d Kathleen recalls. \u201cWell, her self-portrait had all the body parts \u2013 bones, organs. It was really interesting. I framed it and it\u2019s hanging in her office now.\u201d<\/p>\n

\"\"
UCHealth Lone Tree Health Center charge nurse Kathleen Cleary, RN (left), and her daughter Allison Cleary, all dolled up in Sweden, holding Allison\u2019s trophy, her award for winning the Science & SciLifeLab Prize for Young Scientists.<\/figcaption><\/figure>\n

Although she expanded her interests to include scientific research as well as medicine, Allison has stayed true to her childhood dream. Recently another dream came true, although it wasn\u2019t one she would\u2019ve ever been able to imagine when she was in first grade.<\/p>\n

Game changer<\/strong><\/p>\n

Just after she completed the PhD component of her dual MD\/PhD program at Pennsylvania State University College of Medicine, Allison found out that she had won the prestigious Science & SciLifeLab Prize for Young Scientists<\/a>, awarded to promising early-career scientists who conduct groundbreaking life-science research.<\/p>\n

The grand prize included $30,000, publication of her application essay in the journal Science<\/em>, a trip to Sweden for the Science<\/em> & SciLifeLab Prize ceremony, and attendance at the Nobel Prize Award ceremony. Not too shabby for a career that is only beginning. Allison will finish up her medical degree in May.<\/p>\n

She thought that the prize committee had made an error when they notified her that she won.<\/p>\n

\u201cHonestly, I thought they must have made a mistake when I got the call. But it is a really big honor to have won,\u201d she says.<\/p>\n

Heady stuff<\/strong><\/p>\n

If you\u2019re impressed with Allison Cleary\u2019s prize, wait until you hear about her essay, which is based on her thesis and research. Contest applicants must have received their doctoral degree within the previous two years and the thesis topic must be in one of the following areas: Cell and Molecular Biology, Genomics and Proteomics, Ecology and Environment, or Translational Medicine.<\/p>\n

\"Allison
Allison Cleary being interviewed by Science and SciLifeLab for a video to promote the prize.<\/figcaption><\/figure>\n

Cleary\u2019s Cell and Molecular Biology research investigated how tumor cells communicate with each other to promote tumor growth. While a graduate student in the laboratory of Edward Gunther, a professor of medicine at The Huck Institutes of Life Sciences at Penn State, Cleary studied mouse models of breast cancer. She focused on new research that showed multiple tumor cell subpopulations coexist within individual human breast cancers. Researchers had previously believed that these cell subpopulations competed with each other, with the \u201cfittest\u201d subpopulation influencing the tumor.<\/p>\n

Cleary\u2019s research showed that these cell subpopulations actually cooperate with each other to affect tumor growth.<\/p>\n

\u201cWe were able to identify that some tumors have two distinct populations of tumor cells and that the tumor cell growth depended on interactions between both populations,\u201d she explained. \u201cEither population by itself was unable to grow tumors, but when we mixed the two cell populations together, tumors grew rapidly.\u201d<\/p>\n

She now aims to get accepted into a pathology residency training program on a physician-investigator track, which will incorporate additional research training into the traditional clinical residency training, Cleary says.<\/p>\n

Cleary originally thought she would study musculoskeletal and neuromuscular disorders like muscular dystrophy, as she did when she was in a lab as an undergraduate at the University of Colorado Boulder. But after she did a rotation in a cancer lab in graduate school, she was hooked, and switched gears.<\/p>\n

\u201cI became absolutely fascinated by cancer,\u201d she recalls. \u201cThe fact that our own cells, for some reason, have been hijacked or gone rogue and are now working against us is so interesting.\u201d<\/p>\n

Soiree in Sweden<\/strong><\/p>\n

Kathleen, who has been a nurse for almost 20 years, joined University of Colorado Health last year. She and her husband traveled to Stockholm in last December to attend Allison\u2019s award banquet and ceremony. They had to miss the Nobel Prize ceremony.<\/p>\n

\u201cIt was overwhelming, absolutely overwhelming,\u201d says Kathleen. \u201cShe\u2019s worked very hard throughout these nine years [in her MD\/PhD program] and it\u2019s tremendous recognition for her work. I\u2019m pretty proud of her.\u201d<\/p>\n

For Allison, the time in Stockholm was \u201cone amazing event right after another.\u201d After the Science<\/em> & SciLifeLab Prize presentation, she was on hand for the Nobel Prize presentations, with the King of Sweden in attendance.<\/p>\n

\u201cIt was a once-in-a-lifetime opportunity \u2026 truly a dream come true,\u201d says Allison of mingling with the Nobel Prize winners for chemistry, physics, economics and literature. \u201cI was awestruck. I got to meet Tomas Lindahl, who was one of this year\u2019s chemistry winners.\u201d<\/p>\n

She has since bought some art with her $30,000, but plans to use the majority of it to pay down student loans. She\u2019s most excited, though, that the prize will bring attention to her research.<\/p>\n

\u201cHopefully people will fund these types of projects in the future and it can only do good things, not only for my own career but for this avenue of investigation within cancer research,\u201d says Allison.<\/p>\n

Ultimately, she would like to have her own research lab and continue to do cancer research. Having accomplished so much at such a young age, we can only imagine what the future will bring for Cleary \u2013 and for cancer research as well.<\/p>\n","protected":false},"excerpt":{"rendered":"

Do you remember what you wanted to be when you grew up? Chances are your adult self wound up\u00a0with different ideas than your five-year-old self. Not so for Allison Cleary, the daughter of Lone Tree Health Center charge nurse Kathleen Cleary, RN. 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