{"id":65126,"date":"2022-08-16T08:27:02","date_gmt":"2022-08-16T14:27:02","guid":{"rendered":"https:\/\/www.uchealth.org\/today\/?p=65126"},"modified":"2022-08-16T08:28:01","modified_gmt":"2022-08-16T14:28:01","slug":"spray-on-skin-helps-young-man-regenerate-skin-tissue","status":"publish","type":"post","link":"https:\/\/www.uchealth.org\/today\/spray-on-skin-helps-young-man-regenerate-skin-tissue\/","title":{"rendered":"\u2018Spray-on skin\u2019 helps young man regenerate skin tissue"},"content":{"rendered":"<div style=\"margin-top: 0px; margin-bottom: 0px;\" class=\"sharethis-inline-share-buttons\" ><\/div><figure id=\"attachment_65167\" aria-describedby=\"caption-attachment-65167\" style=\"width: 640px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-65167\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15151143\/web-Louk-Thomas-Candace-Herrera.webp\" alt=\"Louk with mom Candace Herrera at UCHealth University of Colorado Hospital in early August, five months after the bonfire accident and subsequent ReCell and skin-graft surgeries. Photo by Sonya Doctorian for UCHealth.\" width=\"640\" height=\"450\" srcset=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15151143\/web-Louk-Thomas-Candace-Herrera.webp 800w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15151143\/web-Louk-Thomas-Candace-Herrera-300x211.webp 300w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15151143\/web-Louk-Thomas-Candace-Herrera-768x540.webp 768w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15151143\/web-Louk-Thomas-Candace-Herrera-150x105.webp 150w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15151143\/web-Louk-Thomas-Candace-Herrera-200x141.webp 200w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><figcaption id=\"caption-attachment-65167\" class=\"wp-caption-text\">Louk Thomas with mom Candace Herrera at UCHealth University of Colorado Hospital in early August, five months after the bonfire accident and subsequent ReCell and skin-graft surgeries. Photo by Sonya Doctorian, UCHealth.<\/figcaption><\/figure>\n<p>The gasoline can was about empty as the backyard bonfire got going, and Louk Thomas made the mistake of shaking out its last dribbles over the flames. Fumes exploded as if inside an engine\u2019s cylinder. The fire scorched his hands, arms, and face. When the smoke cleared, 30% of his body had been burned. Louk took a shower, his chief worry being what his mom would say when she got home.<\/p>\n<p>If that seems a boyish concern given the gravity of the moment, well, it was: Louk (pronounced \u201cLuke\u201d) was 15 years old on that evening this past February \u2013 even if, at 5-foot-11 and more than 200 pounds, he didn\u2019t look it.<\/p>\n<p>His mom, Candace Herrera, thought only this: My son needs to get to a hospital.<\/p>\n<p>Doctors at the hospital near the Herrera home in Farmington, N.M., saw that Louk needed specialist burn care. Louk and his mom were soon on a medevac flight to the <a href=\"https:\/\/www.uchealth.org\/locations\/uchealth-burn-center-anschutz-medical-campus\/\">UCHealth Burn and Frostbite Center<\/a> on the Anschutz Medical Campus in Aurora. They arrived at 1:30 a.m., and Louk immediately received critical care to stabilize him and care for his wounds under the direction of his surgeon <a href=\"https:\/\/www.uchealth.org\/provider\/arek-wiktor-md-surgery\/\">Dr. Arek Wiktor<\/a>, the Burn Center\u2019s medical director.\u00a0 Typically, those burns would feature skin grafts harvested from Louk\u2019s own thighs, shoulders, and back. And while Louk would receive traditional skin grafts on his hands, arms, and elsewhere, his face would benefit from a treatment seemingly straight out of science fiction: spray-on skin.<\/p>\n<figure id=\"attachment_65144\" aria-describedby=\"caption-attachment-65144\" style=\"width: 400px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-65144\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104152\/web-Louk-Thomas-bandages-ed.webp\" alt=\"Louk all bandaged up after his spray-on skin treatment. Photo courtesy of Candace Herrera.\" width=\"400\" height=\"533\" srcset=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104152\/web-Louk-Thomas-bandages-ed.webp 750w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104152\/web-Louk-Thomas-bandages-ed-225x300.webp 225w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104152\/web-Louk-Thomas-bandages-ed-113x150.webp 113w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104152\/web-Louk-Thomas-bandages-ed-200x267.webp 200w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><figcaption id=\"caption-attachment-65144\" class=\"wp-caption-text\">Louk bandaged up after his spray-on skin treatment. Photo courtesy of Candace Herrera.<\/figcaption><\/figure>\n<p><a id=\"\" href=\"https:\/\/avitamedical.com\/product\/\" target=\"_blank\" rel=\"noopener\">ReCell<\/a>, as this spray-on skin is called, is very much real, and it\u2019s based on U.S. Food and Drug Administration (FDA)-approved science developed by California-based Avita Medical. Instead of harvesting skin from one part of the body and using it to cover another, ReCell\u2019s approach involves taking a small skin sample and then chemically and physically filtering out the <a id=\"\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7699912\/\" target=\"_blank\" rel=\"noopener\">keratinocytes<\/a>, <a id=\"\" href=\"https:\/\/www.genome.gov\/genetics-glossary\/Fibroblast\" target=\"_blank\" rel=\"noopener\">fibroblasts<\/a>, and <a id=\"\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3834696\/\" target=\"_blank\" rel=\"noopener\">melanocytes<\/a>, all which play critical roles in skin-tissue regeneration. Those end up in a solution that\u2019s then sprayed over the area where skin should be. It all happens in the operating room.<\/p>\n<p>\u201cIt\u2019s kind of like if you were to have a field and plow it, and then plant some seeds, those are the new skin cells\u201d Wiktor said.<\/p>\n<h2><strong>&#8216;Spray-on skin&#8217;<\/strong><\/h2>\n<p>FDA-approved in September 2018, ReCell has shown to be most effective with certain types of burns \u2013 in particular, <a id=\"\" href=\"https:\/\/www.medicalnewstoday.com\/articles\/325189\" target=\"_blank\" rel=\"noopener\">second-degree burns<\/a>. While Louk had <a id=\"\" href=\"https:\/\/www.medicalnewstoday.com\/articles\/third-degree-burns\" target=\"_blank\" rel=\"noopener\">third-degree burns<\/a> on his hands, arms, and elsewhere, his facial burns were deep second, nearly third degree. Wiktor would apply traditional skin grafts to the third-degree burns; ReCell would be the best option for the lesser burns on Louk\u2019s face, the surgeon decided, and for good reasons.<\/p>\n<p>Skin grafts take three to four weeks to heal; ReCell\u2019s \u201cseeds\u201d regrow skin in about half that time. Also, ReCell doesn\u2019t require daily dressing changes, which are painful and can lead to significant scarring. Those differences can mean less time in the hospital and fewer pain medications. Perhaps most strikingly, a postage-stamp-size biopsy of healthy skin liquified and sprayed on can cover an area 80 times larger than the biopsy itself. With skin grafts, one can achieve at best a roughly 6:1 coverage ratio, Wiktor says.<\/p>\n<p>Another benefit: Skin-graft donor sites are themselves wounds that must heal, and ReCell means fewer of them with smaller footprints.<\/p>\n<h2><strong>Wound healing and burn recovery<\/strong><\/h2>\n<p>Louk\u2019s facial bandages stayed on for five days after the spray-on skin treatment, during which, as Herrera put it, \u201cHe looked like the Michelin Man.\u201d<\/p>\n<figure id=\"attachment_65143\" aria-describedby=\"caption-attachment-65143\" style=\"width: 400px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-65143\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104142\/web-Louk-bandages-off-ed.webp\" alt=\"Louk shortly after his facial bandages were removed. Photo courtesy of Candace Herrera.\" width=\"400\" height=\"286\" srcset=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104142\/web-Louk-bandages-off-ed.webp 800w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104142\/web-Louk-bandages-off-ed-300x214.webp 300w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104142\/web-Louk-bandages-off-ed-768x548.webp 768w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104142\/web-Louk-bandages-off-ed-150x107.webp 150w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104142\/web-Louk-bandages-off-ed-200x143.webp 200w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><figcaption id=\"caption-attachment-65143\" class=\"wp-caption-text\">Louk shortly after his facial bandages were removed. Photo courtesy of Candace Herrera.<\/figcaption><\/figure>\n<p>Louk approached his treatment with the toughness of the cowboy he is (he <a id=\"\" href=\"https:\/\/rodeonews.com\/association\/meet-the-member-louk-thomas\/\" target=\"_blank\" rel=\"noopener\">competes<\/a> in team roping). Did he wish he hadn\u2019t been burned? Yes. Was he dwelling on the mistake?<\/p>\n<p>\u201cI\u2019m alive. I live day-by-day,\u201d Louk said. \u201cYou can\u2019t change the past, so you might as well get on with your life.\u201d<\/p>\n<p>But this cowboy was still a boy undergoing a total of 10 skin grafts through eight surgeries, and he was a long way from home. He wanted his mom close. For many of the nights over the seven-and-a-half weeks that Louk stayed in the Burn Center, Herrera wore a gown, gloves and mask for infection control while sleeping in the room with her son.<\/p>\n<p>\u201cYou just hope that your kid\u2019s OK,\u201d she said later.<\/p>\n<p>ReCell is now considered for every burn patient at the UCHealth Burn and Frostbite Center, Wiktor says. It can be used to speed the healing of donor sites and the gaps between sections of grafted skin when it\u2019s slitted and stretched to apply to burn wounds several times larger than the donor site.<\/p>\n<p>\u201cWe use this technique at least once or twice a week, because it\u2019s such a powerful tool for us to achieve excellent wound coverage using as little graft as possible,\u201d Wiktor said.<\/p>\n<figure id=\"attachment_65141\" aria-describedby=\"caption-attachment-65141\" style=\"width: 400px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-65141\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104131\/web-Arek-Wiktor-Recell-size-demo.webp\" alt=\"Dr. Arek Wiktor comparing the size of harvested skin a single ReCell kit can process with the spray coverage that kit can produce. Each kit can convert four 3-by-2 centimeter skin biopsies to cover an area that might otherwise require donor grafts as large as a patient\u2019s entire back. Photo by Sonya Doctorian for UCHealth.\" width=\"400\" height=\"327\" srcset=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104131\/web-Arek-Wiktor-Recell-size-demo.webp 800w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104131\/web-Arek-Wiktor-Recell-size-demo-300x245.webp 300w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104131\/web-Arek-Wiktor-Recell-size-demo-768x627.webp 768w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104131\/web-Arek-Wiktor-Recell-size-demo-150x122.webp 150w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104131\/web-Arek-Wiktor-Recell-size-demo-200x163.webp 200w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><figcaption id=\"caption-attachment-65141\" class=\"wp-caption-text\">Dr. Arek Wiktor comparing the size of harvested skin that a single ReCell kit can process with spray coverage.\u00a0 Each kit can convert four 3-by-2 centimeter skin biopsies to cover an area that might otherwise require donor grafts as large as a patient\u2019s entire back. Photo by Sonya Doctorian, UCHealth.<\/figcaption><\/figure>\n<p>Louk went home the third week in April. By then, he was asking his Burn Center caregivers when he might get back to team roping.<\/p>\n<p>\u201cThey told me, \u2018You won\u2019t rope this summer,\u201d Louk recalled. \u201cI said, \u2018Watch me.\u2019\u201d<\/p>\n<p>On July 4, he was team roping again at an event in Durango. Despite precautions such as compression sleeves and gloves, the fresh skin on his thighs didn\u2019t take kindly to it and blistered, he says. Small penance for getting back to his passion so quickly.<\/p>\n<h2><strong>\u2018Like family\u2019<\/strong><\/h2>\n<p>Just over five months from the accident, Louk, his mom, and stepdad Rusty Herrera now drive the seven hours from Farmington to Aurora every six weeks for series of six laser treatments to smooth out his facial scars and improve their texture and flexibility. On a recent visit, Herrera said, \u201cI still see my son when I look at him. Had we done the full skin grafts, I don\u2019t think he would look the same. I\u2019m so thankful.\u201d<\/p>\n<figure id=\"attachment_65140\" aria-describedby=\"caption-attachment-65140\" style=\"width: 400px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-65140\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104125\/web-Louk_Thomas.webp\" alt=\"15-year-old Louk Thomas suffered burns to more than 30 percent of his body after an accident around a campfire back in February. The New Mexico teen was airlifted to UCHealth University of Colorado Hospital Burn and Frostbite Center, where he underwent nearly a dozen surgeries, including one involving innovative \u201cspray-on skin.\u201d\u00a0Photo by Sonya Doctorian for UCHealth.\" width=\"400\" height=\"260\" srcset=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104125\/web-Louk_Thomas.webp 800w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104125\/web-Louk_Thomas-300x195.webp 300w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104125\/web-Louk_Thomas-768x499.webp 768w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104125\/web-Louk_Thomas-150x98.webp 150w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2022\/08\/15104125\/web-Louk_Thomas-200x130.webp 200w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><figcaption id=\"caption-attachment-65140\" class=\"wp-caption-text\">Louk Thomas, 15, suffered burns to more than 30% of his body after an accident around a campfire back in February. The New Mexico teen was airlifted to UCHealth University of Colorado Hospital Burn and Frostbite Center, where he underwent nearly a dozen surgeries, including one involving innovative \u201cspray-on skin.\u201d Photo by Sonya Doctorian, UCHealth.<\/figcaption><\/figure>\n<p>Both she and Louk describe the Burn Center team as \u201clike family.\u201d In addition to the care they delivered, staff had reached out to country music star Tim McGraw during Louk\u2019s stay. McGraw recorded a short video for Louk, saying the young cowboy should listen to his doctors and keep his chin up.<\/p>\n<p>Herrera brings along Crumbl Cookies or candy on their visits to the Anschutz Medical Campus, she says. She can\u2019t truly reciprocate for what the team has done for Louk, she says, \u201cbut maybe a cookie or a sweet will brighten their day.\u201d<\/p>\n<p>\u201cI\u2019m eternally grateful for Dr. Wiktor and his whole team,\u201d Herrera said.<\/p>\n<p>Louk is just as thankful.<\/p>\n<p>\u201cThese people helped me so much,\u201d he said. \u201cThey\u2019re still helping me today.\u201d<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The gasoline can was about empty as the backyard bonfire got going, and Louk Thomas made the mistake of shaking out its last dribbles over the flames. Fumes exploded as if inside an engine\u2019s cylinder. The fire scorched his hands, arms, and face. When the smoke cleared, 30% of his body had been burned. Louk [&hellip;]<\/p>\n","protected":false},"author":23,"featured_media":65167,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[5],"tags":[4293],"class_list":["post-65126","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-innovative-care","tag-uchealth-burn-and-frostbite-center"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>&#039;Spray-on skin&#039; helps young man regenerate skin tissue - 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