{"id":70009,"date":"2023-05-15T09:24:30","date_gmt":"2023-05-15T15:24:30","guid":{"rendered":"https:\/\/www.uchealth.org\/today\/?p=70009"},"modified":"2025-01-15T09:35:03","modified_gmt":"2025-01-15T16:35:03","slug":"community-input-sought-for-trauma-study-at-uchealth-memorial-hospital-central","status":"publish","type":"post","link":"https:\/\/www.uchealth.org\/today\/community-input-sought-for-trauma-study-at-uchealth-memorial-hospital-central\/","title":{"rendered":"Community input sought for trauma study at UCHealth Memorial Hospital Central"},"content":{"rendered":"<div style=\"margin-top: 0px; margin-bottom: 0px;\" class=\"sharethis-inline-share-buttons\" ><\/div><figure id=\"attachment_54503\" aria-describedby=\"caption-attachment-54503\" style=\"width: 640px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-54503 size-large\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2020\/02\/17123854\/UCHealth_Memorial_Hospital_Central_Sunrise-scaled-1024x684.webp\" alt=\"A photo of UCHealth Memorial Hospital Central in Colorado Springs.\" width=\"640\" height=\"428\" srcset=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2020\/02\/17123854\/UCHealth_Memorial_Hospital_Central_Sunrise-scaled-1024x684.webp 1024w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2020\/02\/17123854\/UCHealth_Memorial_Hospital_Central_Sunrise-scaled-300x200.webp 300w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2020\/02\/17123854\/UCHealth_Memorial_Hospital_Central_Sunrise-scaled-768x513.webp 768w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2020\/02\/17123854\/UCHealth_Memorial_Hospital_Central_Sunrise-scaled-150x100.webp 150w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2020\/02\/17123854\/UCHealth_Memorial_Hospital_Central_Sunrise-scaled-200x134.webp 200w, https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2020\/02\/17123854\/UCHealth_Memorial_Hospital_Central_Sunrise-scaled.webp 1498w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><figcaption id=\"caption-attachment-54503\" class=\"wp-caption-text\">UCHealth Memorial Hospital Central<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<p>UCHealth Memorial Hospital Central is seeking community input for a clinical trial to determine whether a blood clotting drug, given soon after arrival in the emergency department, can improve survival.<\/p>\n<p>The virtual meetings are:<\/p>\n<ul>\n<li>4 p.m. June 15, 2023. Use this link to join the meeting: <a href=\"https:\/\/uab-mc.zoom.us\/j\/87349416221\">https:\/\/uab-mc.zoom.us\/j\/87349416221<\/a><\/li>\n<li>Noon June 23, 2023. Use this link to join the meeting: <a href=\"https:\/\/uab-mc.zoom.us\/j\/86206059718\">https:\/\/uab-mc.zoom.us\/j\/86206059718<\/a><\/li>\n<\/ul>\n<p><strong>For more information, see below<\/strong>:<\/p>\n<p>Bleeding out is the most common cause of preventable death after an injury. Researchers at UCHealth Memorial Hospital Central are asking for community input on whether they should participate in an international study to see if a blood clotting drug, given soon after arrival in the emergency department, can improve survival.<\/p>\n<p>Kcentra\u00ae (or 4-factor Prothrombin Complex Concentrate) is a Food and Drug Administration (FDA)-approved drug and is currently used to reverse the effects of medications given to \u201cthin\u201d the blood for patients who experience bleeding and\/or require surgery.<\/p>\n<p>The Trauma and Prothrombin Complex Concentrate (TAP) Trial will evaluate the effectiveness of Kcentra\u00ae, in addition to all standard care, in injured patients predicted to require a large-volume blood transfusion.<\/p>\n<p>\u201cThere is evidence that Kcentra\u00ae may reduce the chance of dying in injured patients who are not on blood-thinning medications,\u201d explains Dr. Thomas Schroeppel, a trauma surgeon at Memorial Hospital Central.<\/p>\n<p>\u201cThe standard treatment of injured patients who are bleeding involves the transfusion of different types of blood products, as well as the use of medications to help the blood clot better, along with surgery to stop the bleeding. But even with these treatments, up to 30% of patients suffering from a serious traumatic injury die,\u201d\u00a0said Dr. Schroeppel. \u201cFinding a way to improve that survival rate is our highest priority here at Memorial Hospital Central.\u201d<\/p>\n<p>Patients in this study will have suffered a serious and potentially life-threatening injury, causing significant blood loss and requiring immediate lifesaving interventions. These types of injuries occur unexpectedly, and it will not be possible for most people to sign up to participate ahead of time. Most patients will be unconscious, unable to speak or hear, and too sick to consent to immediate treatment or participation in the study.<\/p>\n<p>If the community feedback is positive and an independent review board (IRB) approves the study at Memorial Hospital Central, then the hospital will participate in this trial. Community members who do not want to participate can request a bracelet indicating this. If feasible, doctors will consent patients who fit the study criteria. If consent is not feasible, patients who fit the criteria will be automatically enrolled without their individual consent if they are not wearing an opt-out bracelet.<\/p>\n<p>The TAP trial will be conducted in about 120 leading trauma centers in several countries and will include 8,000 patients, making it the second-largest trauma trial ever conducted. Researchers estimate the trial will begin in late-summer 2023 and last until 2026, and is funded by CSL Behring, a global biotherapeutics leader that makes Kcentra\u00ae.<\/p>\n<p>\u201cThe results of this study have the potential to change the way trauma patients are treated,\u201d said Dr. Schroeppel. \u201cIf we can determine that Kcentra\u00ae is safe and effective for trauma patients, we can transform the standard of care for bleeding trauma patients and save thousands of lives.\u201d<\/p>\n<p>The researchers are asking for feedback from the Pikes Peak region community about this study to help determine whether the community wants the hospital to participate in this study. Please consider completing a very brief anonymous survey hosted by the local study site. To complete the anonymous survey on your thoughts about this exception from informed consent study, please click <a id=\"\" href=\"https:\/\/uab.co1.qualtrics.com\/jfe\/form\/SV_7OtcEHo1o7CaOnI\">here<\/a>.<\/p>\n<p>The researchers invite all interested in learning more about the TAP Trial at UCHealth Memorial Hospital Central to attend an online community forum. Pre-registration is not required. Dates, times and ZOOM links may be found on Memorial Hospital Central\u2019s study website.<\/p>\n<p>Questions may also be directed UCHealth Memorial Hospital\u2019s Trauma Research program at: TraumaResearchSouth@uchealth.org<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; UCHealth Memorial Hospital Central is seeking community input for a clinical trial to determine whether a blood clotting drug, given soon after arrival in the emergency department, can improve survival. The virtual meetings are: 4 p.m. June 15, 2023. Use this link to join the meeting: https:\/\/uab-mc.zoom.us\/j\/87349416221 Noon June 23, 2023. Use this link [&hellip;]<\/p>\n","protected":false},"author":26,"featured_media":54504,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[8],"tags":[167],"class_list":["post-70009","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-clinical-trials"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Community input sought for trauma study at UCHealth Memorial Hospital Central - 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